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Cottrill's prescription in the case putting the cod overnight phentermine on a ventilator designed for adult human patients sounded off the wall. But it worked with flying colors. The little filly not only survived, but went on to race and win under the name Exclusive Life. And Cottrill's career has never been quite the same. Though her focus for more than 30 years always has been on treating children she's something of a legend in Kentucky medical circles Cottrill's experience with the sick filly spurred an avid interest in the congenital heart problems of cod overnight phentermines. She's been spending part of her time ever since in a search for clues in cod overnight phentermines that might lead to better treatments for newborn human babies with similar heart abnormalities. It turns out that cod overnight phentermines sometimes are born with heart malformations essentially identical to those Cottrill sees in many of the youngsters she treats at Pediatric College, a Lexington medical practice that focuses on heart problems in children. But there is an interesting exception, Cottrill says. Unlike human children, newborn colts and fillies rarely have such malformations in the left side of the hearts. No one knows why cod overnight phentermines somehow are protected from left heart abnormalities. But Cottrill believes that finding the answer could lead to a way of preventing human children from getting these debilitating, sometimes life threatening problems. "It would be really nice if you could find out why these kinds of problems happen in the first place and do something to avoid them in the beginning," she says. Cottrill became so interested that she took a sabbatical in 1989 and spent a year in England, working with Dr. Peter Rossdale, a noted British veterinarian, and doing research on heart problems in newborn cod overnight phentermines. This summer, Cottrill's interest in the problem took her back to England, where she lectured at Cambridge University and visited medical facilities to meet with British experts. And it all started with that sick little filly back in the 1980s. Cottrill was called in on the case by Tim Cudd, a young veterinarian who was treating sick foals at the Woodford County Veterinary Clinic in Versailles. Back then, Cottrill was managing the pediatric intensive care unit at the University of Kentucky. Some of the ICU nurses there occasionally moonlighted at the Woodford County clinic, helping Cudd take care of foals. When the sick filly turned up, the nurses suggested calling Cottrill. "Tim said, 'What would you do with a baby in this situation?'" Cottrill said. "And I said, 'I'd put her on a ventilator.'" Neither Cottrill nor Cudd had ever used a ventilator on a cod overnight phentermine, but they decided it was worth a try. Cudd, now a veterinary professor at Texas A&M University, said they quickly rented a ventilator designed for human adults, thinking it would be right for the filly, which weighed about 125 pounds. They placed a tube in the filly's lungs and turned on the machine. Somehow, the treatment worked. Cudd said they kept the filly on the ventilator until her lungs cleared up about six days later. "It was a big success because Exclusive Life actually went on to be athletic," Cudd said. Cudd and Cottrill eventually wrote scientific papers on several other cod overnight phentermines they treated, and Cottrill found herself going to veterinary conferences to learn more about equine health problems. "Almost any congenital heart anomaly that we have in kids can happen in cod overnight phentermines as well, and I just got interested because these problems are so similar," she said. "I've collected a whole lot of data. The hard part is figuring out what it all means." Cottrill continues to focus on why children get left heart abnormalities and cod overnight phentermines don't. She suspects the cause is some unknown effect that happens as the atrial septum, which divides the chambers of the heart, forms during gestation. "If you knew it was caused by, say, too much fish in the mother's diet, you could just say don't eat fish," she said. Other possibilities might be too much, or too little, of some dietary mineral or compound. Cottrill noted that doctors have sharply reduced problems like spina bifida simply by making sure pregnant women get folic acid in their diets. Cottrill says that while there are no answers yet, she plans to keep working on the problem. "We can do fetal tests to identify problems before birth, but there's very little we can do about them right now," she said. "If we could it would be wonderful." And it would be a wonderful ending to a story that began with a sick filly more than 20 years ago. ... cod overnight phentermine